Reporting Sex and Sex Differences in Preclinical Studies
نویسندگان
چکیده
منابع مشابه
Perils and pitfalls of reporting sex differences.
The idea of sex differences in the brain both fascinates and inflames the public. As a result, the communication and public discussion of new findings is particularly vulnerable to logical leaps and pseudoscience. A new US National Institutes of Health policy to consider both sexes in almost all preclinical research will increase the number of reported sex differences and thus the risk that res...
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Both sex (i.e., biological construct of male and female) and gender (i.e., social construct of masculine and feminine) impact the pathogenesis of diseases, including those caused by microbial infections. Following the 2015 NIH policy for consideration of sex as a biological variable in preclinical research, in 2018, authors of papers published in primary-research American Society for Microbiolo...
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Background: The purpose of this study was to examine symptoms of acute coronary syndrom (ACS) with resect to sex differences. Methods: This comparative cross-sectional study was performed on patients older than 20 years with ACS who were hospitalized at cardiac wards. Sampling was performed through stratified sampling on the basis of sex. Five hundred male and female patients me...
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Preclinical research is fundamental for the advancement of biomedical sciences and enhancing healthcare. Considering sex differences in all studies throughout the entire biomedical research pipeline is necessary to adequately inform clinical research and improve health outcomes. However, there is a paucity of information to date on sex differences in preclinical work. As of 2009, most (about 80...
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Swayed by the clear distinction between male and female genitalia, the question of how far these categories extend into human biology has attracted humans for centuries. This question is sometimes being framed as whether the effects of sex are restricted to the genital organs or penetrate the entire organism. Here I argue that the two questions are not equivalent and that whereas the answer to ...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2018
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.118.311717